Video Experimental Relacionado
Updated: May 3, 2026
07:03
The Ingestion of Fluorescent, Magnetic Nanoparticles for Determining Fluid-uptake Abilities in Insects
Published on: December 20, 2017
5.8K
El paso de las partículas inhaladas a la circulación sanguínea en humanos
A Nemmar1, P H M Hoet, B Vanquickenborne
1Laboratory of Pneumology (Lung Toxicology, Katholieke Universiteit Leuven, Leuven, Belgium.
Circulation
|January 30, 2002
Resumen
Las partículas ultrafinas inhaladas entran rápidamente en el torrente sanguíneo, lo que podría explicar la contaminación del aire.
Área de la Ciencia:
- Salud Ambiental Salud del medio ambiente.
- Toxicología Toxicología.
- Investigaciones Cardiovasculares Investigación Cardiovascular Investigaciones Cardiovasculares
Sus antecedentes:
- La contaminación atmosférica por partículas está relacionada con las enfermedades cardiovasculares.
- Los mecanismos detrás de estos efectos siguen sin estar claros.
Objetivo del estudio:
- Para investigar la circulación sistémica de las partículas ultrafinas inhaladas.
- Para determinar la velocidad y el alcance de la translocación de partículas.
Principales métodos:
- Voluntarios sanos inhalaron (99m) partículas ultrafinas de carbono etiquetadas con tecnecio (<100 nm).
- La radiactividad en la sangre y la distribución corporal se midió utilizando cámaras gamma.
- Muestras de sangre analizadas mediante cromatografía de capa delgada.
Principales resultados:
- Radioactividad detectada en la sangre dentro de 1 minuto después de la inhalación.
- El pico de radioactividad en la sangre se observa entre 10-20 minutos, sostenido durante 60 minutos.
- Se detectó tanto tecnecio unido a partículas como tecnecio oxidado en la sangre; el hígado mostró una radioactividad significativa.
Conclusiones:
- Las partículas de carbono ultrafinas inhaladas entran rápidamente en la circulación sistémica.
- Esta rápida translocación puede explicar los efectos extrapulmonares de la contaminación del aire.
Videos de Conceptos Relacionados
01:16The Respiratory System
76.9K
The respiratory system is comprised of the organs that enable breathing. Air enters the nostrils and mouth, followed by the pharynx (throat) and larynx (voice box), which lead to the trachea (windpipe). In the thoracic cavity, the trachea splits into two bronchi that allow air to enter the lungs. The bronchi split into progressively smaller bronchioles and terminate in small groups of tiny sacs in the lungs called alveoli, where gas exchange occurs.
76.9K
01:05Breathing
50.6K
The process of breathing, inhaling and exhaling, involves the coordinated movement of the chest wall, the lungs, and the muscles that move them. Two muscle groups with important roles in breathing are the diaphragm, located directly below the lungs, and the intercostal muscles, which lie between the ribs. When the diaphragm contracts, it moves downward, increasing the volume of the thoracic cavity and creating more room for the lungs to expand. When the intercostal muscles contract, the ribs...
50.6K
01:20Infection
11.6K
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
11.6K
01:22Lifecycle of Erythrocytes
5.7K
Erythrocytes, also known as red blood cells, constantly move through blood capillaries. As a result, they damage their plasma membrane due to the continuous friction. Typically, after 100 to 120 days, erythrocytes become rigid and fragile as they wear out. As they pass through small vessels in the spleen and liver, they can get trapped and break apart into fragments.
The resident phagocytic macrophages deal with these damaged cells by engulfing them and separating their globin and heme groups....
The resident phagocytic macrophages deal with these damaged cells by engulfing them and separating their globin and heme groups....
5.7K
01:20Capillaries and Their Types
9.1K
Capillaries, a crucial constituent of the circulatory system, are diminutive vessels with a diameter between 5–10 micrometers, accommodating perfusion to the tissues through the phenomenon known as microcirculation. Through their permeable walls, consisting of an endothelial layer ensconced by a basement membrane and sporadically dispersed smooth muscle fibers, the exchange of substances between the blood and the interstitial fluid becomes plausible. Variance in wall composition exists,...
9.1K
01:25Deglutition
7.7K
Swallowing, otherwise known as deglutition, facilitates the transport of food from the mouth to the stomach. It is a multifaceted process that involves both the tongue and the muscles of the throat and esophagus. Saliva and mucus aid in this process, which takes approximately 4 to 8 seconds for semi-solid or solid food and around 1 second for liquids or very soft food.
Swallowing can be divided into three stages: the voluntary phase, the pharyngeal phase, and the esophageal phase. Although the...
Swallowing can be divided into three stages: the voluntary phase, the pharyngeal phase, and the esophageal phase. Although the...
7.7K