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Mecanismos de la disfunción microcirculatoria coronaria en pacientes con estenosis aórtica y arterias coronarias

Kim Rajappan¹, Ornella E Rimoldi, David P Dutka

¹Medical Research Council Clinical Sciences Centre, Hammersmith Hospital, London, UK.

|January 30, 2002

Resumen

En la estenosis aórtica grave, la microcirculación coronaria se ve afectada, especialmente en el subendocardio del ventrículo izquierdo. Esta disfunción está relacionada con el área y la presión de la válvula aórtica, no solo con el tamaño del músculo cardíaco.

Área de la Ciencia:

Fisiología cardiovascular fisiología cardiovascular.
Imágenes médicas de imágenes médicas.
Ingeniería Biomédica Ingeniería Biomédica.

Sus antecedentes:

La hipertrofia ventricular izquierda (LVH) en la estenosis aórtica (AS) está asociada con la disfunción microcirculatoria coronaria.
La evidencia para las anomalías regionales del flujo sanguíneo miocárdico (FMB) y sus mecanismos en la HLV inducida por AS es limitada.
Este estudio tuvo como objetivo cuantificar las diferencias regionales en la microcirculación e identificar los factores que contribuyen.

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