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La fosfolipasa C gamma 1 es un factor de intercambio fisiológico de nucleótidos de guanina para la GTPasa nuclear

Keqiang Ye1, Bahman Aghdasi, Hongbo R Luo

  • 1Johns Hopkins University School of Medicine, Department of Neuroscience, 725 N. Wolfe Street, Baltimore, Maryland 21205, USA.

Nature
|February 2, 2002
PubMed
Resumen

La fosfolipasa C gamma 1 (PLC-gamma 1) actúa como un factor de intercambio de nucleótidos de guanina (GEF) para PIKE, una GTPasa nuclear. Esta nueva actividad de HAP explica los efectos mitogénicos del PLC-gamma 1.

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