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Updated: Jun 29, 2026

Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists
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Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists

Published on: November 16, 2013

Bases estructurales para el reclutamiento mediado por antagonistas de co-represores nucleares por PPARalpha

H Eric Xu1, Thomas B Stanley, Valerie G Montana

  • 1Nuclear Receptor Discovery Research, GlaxoSmithKline, Research Triangle Park, NC 27709, USA. ex11957@gsk.com

Nature
|February 15, 2002
PubMed
Resumen

Los receptores nucleares reprimen la transcripción génica a través de los co-represores. Este estudio revela la estructura cristalina de un complejo receptor-co-represor nuclear, aclarando un mecanismo conservado para la represión génica.

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