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Requisito del gen de la desaminasa inducida por activación (AID) para la conversión del gen de inmunoglobulina

Hiroshi Arakawa1, Jessica Hauschild, Jean-Marie Buerstedde

  • 1Department of Cellular Immunology, Heinrich-Pette-Institute, Martinistrasse 52, 20251 Hamburg, Germany.

Science (New York, N.Y.)
|February 16, 2002
PubMed
Resumen

El gen de la desaminasa inducida por activación (AID) es crucial para la conversión del gen de la inmunoglobulina (Ig) en las células B. Disrupting AID bloquea la conversión del gen Ig, destacando su papel en todas las modificaciones del gen Ig de las células B.

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