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In Vivo Imaging Systems (IVIS) Detection of a Neuro-Invasive Encephalitic Virus
Published on: December 2, 2012
Encefalitis viral: infecciones conocidas y patógenos emergentes
Richard J Whitley1, John W Gnann
1Department of Pediatrics, Microbiology and Medicine, University of Alabama at Birmingham, USA. R.Whitley@peds.uab.edu
Lancet (London, England)
|February 21, 2002
Resumen
Los avances en el diagnóstico y la prevención de los encefalitos virales, particularmente el herpes y las infecciones enterovirales, están mejorando los resultados de los pacientes. Si bien los tratamientos efectivos siguen siendo limitados, la investigación de nuevas terapias ofrece esperanza para el manejo de estas infecciones del sistema nervioso central.
Área de la Ciencia:
- Neurología Neurología.
- Enfermedades infecciosas Enfermedades infecciosas.
- Virología Virología.
Sus antecedentes:
- Los encefalitos virales son infecciones graves del sistema nervioso central con una morbilidad y mortalidad significativas.
- La comprensión de su patogénesis e historia natural ha avanzado considerablemente.
Objetivo del estudio:
- Revisar los conocimientos actuales sobre los encefalitos virales.
- Para resaltar las infecciones virales emergentes y las opciones de tratamiento disponibles.
Principales métodos:
- Revisión de la literatura científica reciente sobre los encefalitos virales.
- Centrarse en los avances diagnósticos, las estrategias de prevención y las intervenciones terapéuticas.
Principales resultados:
- La reacción en cadena de la polimerasa (PCR) ha mejorado el diagnóstico del herpes y las infecciones enterovirales.
- La vacunación es efectiva para la encefalitis japonesa y la rabia.
- El control de vectores es clave para los arbovirus.
- El aciclovir es eficaz para la encefalitis por herpes simple; otros tratamientos están siendo evaluados.
Conclusiones:
- Avances significativos en la comprensión y el manejo de los encefalitos virales.
- La vacunación y el control de vectores son estrategias de prevención cruciales.
- Las opciones terapéuticas limitadas pero en desarrollo requieren una investigación continua, especialmente para las infecciones emergentes.
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