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High-Pressure NMR Experiments for Detecting Protein Low-Lying Conformational States
04:37

High-Pressure NMR Experiments for Detecting Protein Low-Lying Conformational States

Published on: June 29, 2021

Excitación altamente selectiva en RMN biomolecular por intercambio de frecuencia de una sola transición de

Fabien Ferrage1, Thomas R Eykyn, Geoffrey Bodenhausen

  • 1Département de Chimie, associé au CNRS, Ecole normale supérieure, 24, rue Lhomond, 75231 Paris Cedex 05, France.

Journal of the American Chemical Society
|March 7, 2002
PubMed
Resumen

Los investigadores desarrollaron un nuevo método de RMN biomolecular que utiliza la polarización cruzada para excitar selectivamente pares de espines individuales en las proteínas. Esta técnica mejora la resolución espectral al aprovechar los efectos de estrechamiento de la línea TROSY para mejorar el análisis.

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