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Conformación ligada al receptor de un antagonista de la integrina alfa ((5) beta ((1)) por (15) N-editado 2D

Li Zhang1, Ralph-Heiko Mattern, Timothy I Malaney

  • 1Department of Chemistry and Biochemistry, University of California at San Diego, 6223 Pacific Hall, La Jolla, CA 92093-0343, USA.

Journal of the American Chemical Society
|March 21, 2002
PubMed
Resumen

Este estudio revela la estructura unida de un antagonista alfa ((5) beta ((1)) utilizando (15) N-editado 2D transferido NOE. La comprensión de esta conformación ayuda en el diseño de nuevos fármacos para la metástasis tumoral.

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