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Updated: Oct 1, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

Ensamblaje de eficiencia atómica de carbociclos de tamaño medio con puente de 1,5-oxígeno mediante combinación

Fernando López1, Luis Castedo, José L Mascareñas

  • 1Departamento de Química Orgánica y Unidad Asociada al CSIC, Universidad de Santiago de Compostela, 15782, Santiago de Compostela, Spain.

Journal of the American Chemical Society
|April 19, 2002
PubMed
Resumen

Los catalizadores de rutenio permiten una síntesis eficiente de carbociclos con puentes de oxígeno desafiantes a partir de precursores simples. Este nuevo método proporciona acceso a complejas estructuras de anillos de ocho y nueve miembros que antes eran difíciles de obtener.

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