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Updated: Jul 6, 2026

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells
10:27

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells

Published on: March 9, 2012

SWAP-70 es un factor de intercambio de nucleótidos de guanina que media la señalización de las ondulaciones de la

Masahiro Shinohara1, Yoh Terada, Akihiro Iwamatsu

  • 1Department of Applied Biological Chemistry, Faculty of Agricultural and Life Science, University of Tokyo, Yayoi 1-1-1, Bunkyo-ku, Tokyo 113-8657, Japan.

Nature
|April 19, 2002
PubMed
Resumen

SWAP-70 se identifica como un nuevo factor de intercambio de nucleótidos de Rac-guanina (GEF) que se une al fosfatidilinositol-3,4,5-trisfosfato (PtdIns(3,4,5) P3). Esta proteína media en el revuelo de la membrana celular inducido por el factor de crecimiento y la activación de Rac, independientemente de la señalización Ras.

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