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Sílilformilación intramolecular-crotilsililación en tándem: síntesis altamente eficiente de fragmentos de poliquetido

Michael J Zacuto1, Steven J O'Malley, James L Leighton

  • 1Department of Chemistry, Columbia University, New York, New York 10027, USA.

Journal of the American Chemical Society
|July 4, 2002
PubMed
Resumen

Los investigadores desarrollaron una nueva reacción en tándem para ensamblar de manera eficiente los fragmentos de policetido. Este método crea múltiples estereocentros con alta selectividad, lo que permite la síntesis de moléculas complejas.

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