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Modified Annexin V/Propidium Iodide Apoptosis Assay For Accurate Assessment of Cell Death
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Suicidio por suicidio
1Center for the Study of Suicide, University of South Carolina, Columbia, SC 29208, USA. Maris@sc.edu
Lancet (London, England)
|July 31, 2002
Resumen
El riesgo de suicidio es complejo, a menudo relacionado con trastornos del estado de ánimo. Si bien las escalas de predicción tienen limitaciones, los tratamientos incluyen medicamentos, terapia y, a veces, terapia electroconvulsiva para las personas en riesgo.
Área de la Ciencia:
- La psiquiatría es la psiquiatría.
- La neurociencia es la neurociencia.
- Psicología Clínica Psicología clínica.
Sus antecedentes:
- El suicidio es un tema complejo asociado con los diagnósticos psiquiátricos, particularmente los trastornos del estado de ánimo.
- Los factores de riesgo y de protección identificados para el suicidio muestran consistencia global con algunas variaciones culturales.
- Las escalas estandarizadas de predicción de suicidio producen aproximadamente un 30% de falsos positivos.
Objetivo del estudio:
- Revisar la naturaleza multifacética del suicidio, sus factores de riesgo y las estrategias actuales de prevención y tratamiento.
- Para resaltar los marcadores biológicos y las intervenciones terapéuticas para las personas en riesgo de suicidio.
Principales métodos:
- Revisión de la literatura sobre las causas del suicidio, los factores de riesgo y los elementos de protección.
- Análisis de marcadores biológicos, incluidas las concentraciones de ácido 5-hidroxiindoleacético (5-HIAA) en el líquido cefalorraquídeo (LCR).
- Examen de las modalidades farmacológicas, psicoterapéuticas y de otros tratamientos para la prevención del suicidio.
Principales resultados:
- Las concentraciones reducidas de 5-HIAA en el LCR son el marcador biológico más común en casos de suicidio.
- La prevención del suicidio a menudo implica intervenciones secundarias o terciarias en lugar de primarias.
- El tratamiento comúnmente incluye inhibidores selectivos de la recaptación de serotonina (ISRS), otros medicamentos psicotrópicos, psicoterapia (TCC) y ocasionalmente terapia electroconvulsiva (ECT).
Conclusiones:
- El suicidio es un fenómeno complejo que requiere enfoques de tratamiento multifacéticos.
- La prevención y el manejo efectivos del suicidio integran la comprensión biológica con intervenciones farmacológicas y psicoterapéuticas.
- La hospitalización puede ser necesaria para individuos que representan un peligro para sí mismos.
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