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La MAP quinasa fosfatasa como un locus de flexibilidad en una red de señalización de proteína quinasa activada por

Upinder S Bhalla1, Prahlad T Ram, Ravi Iyengar

  • 1National Center for Biological Sciences, Bangalore 560065 India. bhalla@ncbs.res.in

Science (New York, N.Y.)
|August 10, 2002
PubMed
Resumen

La red de señalización de la proteína quinasa activada por mitógeno (MAPK) 1,2/proteína quinasa C (PKC) puede ser monostable o bistable. La concentración de fosfatasa MAPK determina si el sistema de control del ciclo celular exhibe respuestas sostenidas o agudas a los factores de crecimiento.

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