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La proteína del grupo policombo EZH2 está involucrada en la progresión del cáncer de próstata

Sooryanarayana Varambally1, Saravana M Dhanasekaran, Ming Zhou

  • 1Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA.

Nature
|October 11, 2002
PubMed
Resumen

La sobreexpresión del potenciador del zeste homólogo 2 (EZH2) en el cáncer de próstata se correlaciona con metástasis y mal pronóstico. La inhibición de EZH2 reduce la proliferación de células cancerosas, lo que lo sugiere como un objetivo terapéutico para el cáncer de próstata avanzado.

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