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Updated: Jul 16, 2026

Identifying the Effects of BRCA1 Mutations on Homologous Recombination using Cells that Express Endogenous Wild-type BRCA1
08:53

Identifying the Effects of BRCA1 Mutations on Homologous Recombination using Cells that Express Endogenous Wild-type BRCA1

Published on: February 17, 2011

BRCA1: mecanismos de inactivación e implicaciones para el manejo de los pacientes

Richard D Kennedy1, Jennifer E Quinn, Patrick G Johnston

  • 1Department of Oncology, Cancer Research Centre, Queen's University Belfast, BT9 7AB, Northern Ireland, Belfast, Ireland.

Lancet (London, England)
|October 18, 2002
PubMed
Resumen

Comprender las mutaciones del gen BRCA1 es crucial para la detección temprana del cáncer de mama y de ovario. Esta revisión explora cómo la inactivación del BRCA1 afecta la prevención del cáncer, el pronóstico y la respuesta al tratamiento.

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