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Updated: Jul 22, 2026

Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles
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Preparation of Stable Bicyclic Aziridinium Ions and Their Ring-Opening for the Synthesis of Azaheterocycles

Published on: August 22, 2018

Una síntesis total de novo y enantioselectiva de (-) -laulimalide

Scott G Nelson1, Wing S Cheung, Andrew J Kassick

  • 1Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA. sgnelson@pitt.edu

Journal of the American Chemical Society
|November 15, 2002
PubMed
Resumen

Este estudio detalla la primera síntesis total enantioselectiva de (-) -laulimalida, un agente anticancerígeno natural. El enfoque utiliza nuevas reacciones catalíticas asimétricas de ciclocondensación de halogenuro de acilo-aldehído (AAC) y transformaciones de beta-lactona.

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