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Updated: Jun 11, 2026

Analyzing Protein Dynamics Using Hydrogen Exchange Mass Spectrometry
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Published on: November 29, 2013

Efecto isotópico de amida D/H en el modelo de péptidos alfa helicoidales.

Zhengshuang Shi1, C Anders Olson, Neville R Kallenbach

  • 1Department of Chemistry, New York University, 100 Washington Place, New York, NY 10003, USA.

Journal of the American Chemical Society
|November 21, 2002
PubMed
Resumen

El experimento Cm que mide los efectos de los isótopos de amida D/H revela que las concentraciones de denaturantes tienen un impacto en las mediciones de la estabilidad de las proteínas. El ajuste para la concentración de cloruro de guanidinio (GdmHCl) es crucial para las comparaciones precisas de la estabilidad de las proteínas y las contribuciones de enlaces de hidrógeno.

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