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El ácido acetilsalicílico inhibe la proliferación celular al involucrar la transformación del factor de crecimiento

Santiago Redondo1, Carlos G Santos-Gallego, Patricia Ganado

  • 1Department of Pharmacology, School of Medicine, Universidad Complutense, CIEMAT, Madrid, Spain.

Circulation
|February 5, 2003
PubMed
Resumen

El ácido acetilsalicílico (ASA) inhibe la proliferación vascular de las células del músculo liso, potencialmente a través de la transformación del factor de crecimiento beta (TGF-beta). Este vínculo ASA-TGF-beta sugiere un mecanismo dual en la prevención de la enfermedad coronaria mediante la inhibición de la agregación plaquetaria y el crecimiento de la placa.

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