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Updated: Jul 19, 2026

Steady-state, Pre-steady-state, and Single-turnover Kinetic Measurement for DNA Glycosylase Activity
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Steady-state, Pre-steady-state, and Single-turnover Kinetic Measurement for DNA Glycosylase Activity

Published on: August 19, 2013

La ocratoxina a forma un adducto nucleósido de c8-deoxiguanosina unido al carbono: implicaciones para la reactividad

Jian Dai1, Marcus W Wright, Richard A Manderville

  • 1Department of Chemistry, Wake Forest University, Winston-Salem, North Carolina 27109, USA.

Journal of the American Chemical Society
|March 27, 2003
PubMed
Resumen

La toxina carcinógena ocratoxina A (OTA) puede dañar directamente el ADN al formar un adducto covalente con la desoxiguanosina (dG). Este hallazgo aclara el mecanismo detrás de la OTA.

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