Formación de 14 hélices independiente del medio ambiente en péptidos beta cortos: encontrar un equilibrio entre el

Tami L Raguse1, Jonathan R Lai, Samuel H Gellman

  • 1Department of Chemistry, University of Wisconsin, Madison, Wisconsin 53706, USA.

Resumen

Los investigadores descubrieron que la incorporación de unos pocos residuos rígidos de ácido beta-amino puede estabilizar las estructuras helicoidales en los péptidos beta. Este avance facilita el posicionamiento predecible de la cadena lateral para posibles aplicaciones terapéuticas.

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