Asignaciones de la cadena lateral de los grupos metilo de Ile delta 1 en proteínas de alto peso molecular: una

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iCLIP - Transcriptome-wide Mapping of Protein-RNA Interactions with Individual Nucleotide Resolution
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Published on: April 30, 2011

Vitali Tugarinov1, Lewis E Kay

  • 1Protein Engineering Network Centre of Excellence and the Department of Medical Genetics, University of Toronto, Toronto, Ontario, Canada M5S 1A8.

Journal of the American Chemical Society
|May 8, 2003
PubMed
Resumen

Un nuevo esquema de pulso de RMN 3D, (H) C (CA) NH-COSY, mejora la asignación de los desplazamientos químicos metilo de isoleucina (Ile) en proteínas grandes. Este método mejora la sensibilidad y la resolución en comparación con los esquemas TOCSY para la asignación de metilo.

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