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Updated: Jul 5, 2026

Measuring G-protein-coupled Receptor Signaling via Radio-labeled GTP Binding
10:13

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Published on: June 9, 2017

Los anticuerpos recombinantes contra la pequeña GTPasa Rab6 como sensores de conformación

Clement Nizak1, Solange Monier, Elaine del Nery

  • 1CNRS UMR144, Institut Curie, 26 rue d'Ulm, F75248 Paris Cedex 05, France.

Science (New York, N.Y.)
|May 10, 2003
PubMed
Resumen

Los investigadores desarrollaron sensores de conformación molecular utilizando la pantalla de anticuerpos fagos para rastrear la guanosina trifosfatasa (GTPasa) Rab6. Este método visualiza Rab6-GTP en las células y revela su papel en la modulación de los intermediarios de transporte, ofreciendo una nueva herramienta para estudiar la dinámica molecular.

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