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Mecanismos de la señalización de TGF-beta desde la membrana celular hasta el núcleo del núcleo

Yigong Shi1, Joan Massagué

  • 1Department of Molecular Biology, Princeton University, Washington Road, Princeton, NJ 08544, USA. yshi@molbio.princeton.edu

Cell
|June 18, 2003
PubMed
Resumen

La transformación de la señalización del factor de crecimiento beta (TGF-beta) es crucial para el desarrollo animal. Esta revisión detalla los avances recientes en la comprensión de la activación del receptor TGF-beta, la regulación de la proteína Smad y los mecanismos de expresión génica.

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