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Estructura hexamérica y conjunto del complejo interleucina-6/IL-6 receptor alfa/gp130 complejo

Martin J Boulanger1, Dar-chone Chow, Elena E Brevnova

  • 1Department of Microbiology and Immunology and Department of Structural Biology, Stanford University School of Medicine, Fairchild D319, 299 Campus Drive, Stanford, CA 94305-5124, USA.

Science (New York, N.Y.)
|June 28, 2003
PubMed
Resumen

Este estudio revela la estructura hexamérica del complejo de señalización de la interleucina-6 (IL-6), detallando cómo la IL-6 se conecta con sus receptores. Comprender este ensamblaje es clave para los mecanismos de señalización de citoquinas.

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