Video Experimental Relacionado
Updated: Jun 19, 2026
06:33
A Rapid Protocol for Integrating Extrachromosomal Arrays With High Transmission Rate into the C. elegans Genome
Published on: December 10, 2013
Intercambio de genes por enzimas metabólicas, ¿cómo llegaste a la lista de invitados?
1Department of Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.
Cell
|July 31, 2003
Resumen
El factor de transcripción Oct-1 y el complejo OCA-S controlan la expresión génica de la histona en mamíferos. La gliceraldehído-3-fosfato deshidrogenasa (GADPH) es sorprendentemente vital para la función OCA-S, añadiendo dependencia redox a la transcripción del gen de la histona.
Área de la Ciencia:
- Biología Molecular Biología Molecular
- Regulación genética Reglamento genético.
- La bioquímica es la bioquímica.
Sus antecedentes:
- La expresión génica de la histona es crucial para la replicación y reparación del ADN en las células de los mamíferos.
- El factor de transcripción Oct-1 y su coactivador complejo OCA-S son reguladores conocidos de la transcripción del gen de la histona.
- Los mecanismos moleculares precisos que rigen el complejo OCA-S y su regulación siguen siendo incompletamente entendidos.
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