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Mecanismos genéticos y restricciones que rigen la evolución de los rasgos correlacionados en las moscas drosófilas
Nicolas Gompel1, Sean B Carroll
1Howard Hughes Medical Institute and Laboratory of Molecular Biology, University of Wisconsin, 1525 Linden Drive, Madison, Wisconsin 53706, USA.
Nature
|August 22, 2003
Resumen
Los cambios evolutivos en la pigmentación de la mosca de la fruta y los patrones de tricomas a menudo implican el mismo gen, Bric-à-brac2 (Bab2). Este gen es este gen.
Área de la Ciencia:
- Biología evolutiva Biología evolutiva.
- Genética La genética.
- Biología del desarrollo Biología del desarrollo.
Sus antecedentes:
- La diversidad de rasgos morfológicos entre especies plantea preguntas sobre mecanismos genéticos compartidos y evolución convergente.
- La pigmentación de la mosca de la fruta ofrece un sistema modelo debido a diversos patrones, evolución independiente de rasgos similares y genes reguladores identificados.
Objetivo del estudio:
- Investigar si la diversificación evolutiva y la evolución convergente de los rasgos morfológicos en las moscas de la fruta implican cambios en los mismos genes.
- Examinar el papel del gen Bric-à-brac2 (Bab2) en la evolución de la pigmentación abdominal y los patrones de tricomas en todas las especies de Drosophilinae.
Principales métodos:
- Análisis comparativo de la pigmentación abdominal y los patrones de tricomas en 13 especies de Drosophilinae.
- Examen de la expresión génica de Bric-à-brac2 (Bab2) en relación con los patrones morfológicos observados.
Principales resultados:
- Las modificaciones en la expresión de Bab2 con frecuencia se correlacionan con una pigmentación diversa e independientemente evolucionada y patrones de tricomas.
- En algunas especies, los cambios de expresión de Bab2 están vinculados a patrones de tricomas conservados, lo que sugiere que puede ser omitido para la nueva evolución de la pigmentación.
Conclusiones:
- El locus Bric-à-brac2 (Bab2) juega un papel importante tanto en la diversificación como en la convergencia de los rasgos morfológicos de la mosca de la fruta.
- Las restricciones evolutivas en los rasgos correlacionados pueden conducir a la elusión de genes reguladores clave como Bab2 para la formación de nuevos patrones.
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