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Updated: Jun 24, 2026

Isolation and Kv Channel Recordings in Murine Atrial and Ventricular Cardiomyocytes
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El polimorfismo en el gen de la subunidad modificadora de la ligasa glutamato-cisteína está asociado con el deterioro

Shin-ichi Nakamura1, Seigo Sugiyama, Daisuke Fujioka

  • 12nd Department of Internal Medicine, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, 1110 Shimokato, Nakakoma-gun, Yamanashi, 409-3898 Japan.

Circulation
|September 17, 2003
PubMed
Resumen

La variante -588T en el gen GCLM deteriora la bioactividad del óxido nítrico (NO) endotelial, afectando la función de la arteria coronaria. Este factor genético está relacionado con la reducción de la función vasomotriz y puede influir en el riesgo de enfermedad arterial coronaria.

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