Degeneración in vitro de las neuronas postmitóticas que sobreexpresan el precursor de la proteína amiloide de

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Imaging the Intracellular Trafficking of APP with Photoactivatable GFP
07:55

Imaging the Intracellular Trafficking of APP with Photoactivatable GFP

Published on: October 17, 2015

K Yoshikawa1, T Aizawa, Y Hayashi

  • 1Department of Molecular Biology, Tokyo Institute of Psychiatry, Japan.

Nature
|September 3, 1992
PubMed
Resumen

La sobreexpresión del precursor de la proteína amiloide beta/A4 (APP) en las neuronas conduce a su degeneración. El procesamiento aberrante de APP genera fragmentos que pueden contribuir a la patología de la enfermedad de Alzheimer.

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