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Updated: Jul 16, 2026

Hydrophobic Salt-modified Nafion for Enzyme Immobilization and Stabilization
11:16

Hydrophobic Salt-modified Nafion for Enzyme Immobilization and Stabilization

Published on: July 11, 2012

Un nuevo inhibidor de la nitrilhidratasa tipo Fe: 2-cian-2-propilhidroperoxido

Masanari Tsujimura1, Masafumi Odaka, Hiroshi Nakayama

  • 1Biomolecular Characterization Division, RIKEN (The Institute of Physical and Chemical Research), 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.

Journal of the American Chemical Society
|September 18, 2003
PubMed
Resumen

Una nueva impureza, el hidroperoxido de 2-ciano-2-propilo (Cpx), en el isobutironitril inhibe irreversiblemente la nitrile hidratasa (NHasa) mediante la oxidación de un residuo clave de cisteína. Esta oxidación inactiva la enzima, destacando la importancia de la estructura -SOH para la actividad catalítica.

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