Video Experimental Relacionado

Updated: Jul 13, 2026

Lung Tumor Cell Recruitment Assay
04:28

Lung Tumor Cell Recruitment Assay

Published on: February 26, 2019

El factor de necrosis tumoral alfa activa la vía de transducción de la señal de la esfingomielina en un sistema libre

K A Dressler1, S Mathias, R N Kolesnick

  • 1Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, NY 10021.

Science (New York, N.Y.)
|March 27, 1992
PubMed
Resumen

La señalización del factor de necrosis tumoral alfa (TNF-alfa) implica la hidrólisis de la esfingomielina a la ceramida y la activación de una proteína quinasa activada por la ceramida. Esta cascada, demostrada en un sistema libre de células, sugiere una nueva vía de transducción de señales TNF-alfa.

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