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La fosfolipasa C-beta 1 es una proteína activadora de la GTPasa para Gq/11, su regulador fisiológico

G Berstein1, J L Blank, D Y Jhon

  • 1Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas 75235-9041.

Cell
|August 7, 1992
PubMed
Resumen

La fosfolipasa C-beta 1 (PLC-beta 1) actúa como una proteína activadora de la GTPasa (GAP) para Gq/11, acelerando la hidrólisis del GTP. Este hallazgo explica cómo la señalización de la proteína G se desactiva rápidamente en condiciones fisiológicas.

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