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La expresión dependiente de Pit-1 del receptor para el factor de liberación de la hormona del crecimiento media el

C Lin1, S C Lin, C P Chang

  • 1Eukaryotic Regulatory Biology Program, University of California, San Diego.

Nature
|December 24, 1992
PubMed
Resumen

Las mutaciones en Pit-1 impiden el desarrollo de células pituitarias en ratones enanos. Este estudio identifica el receptor del factor de liberación de la hormona del crecimiento (GRF), crucial para el crecimiento de las células pituitarias, y vincula su ausencia con la deficiencia de Pit-1.

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