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Updated: Jul 19, 2026

Gene-environment Interaction Models to Unmask Susceptibility Mechanisms in Parkinson's Disease
08:09

Gene-environment Interaction Models to Unmask Susceptibility Mechanisms in Parkinson's Disease

Published on: January 7, 2014

El polimorfismo del gen de la debrisoquina hidroxilasa y la susceptibilidad a la enfermedad de Parkinson

C A Smith1, A C Gough, P N Leigh

  • 1Imperial Cancer Research Fund Molecular Pharmacology Group, George Square, Edinburgh, UK.

Lancet (London, England)
|June 6, 1992
PubMed
Resumen

Las variaciones genéticas en el gen del citocromo P450 CYP2D6 aumentan el riesgo de enfermedad de Parkinson. Los metabolizadores pobres de este gen muestran un riesgo 2,54 veces mayor, lo que sugiere un vínculo entre los factores ambientales y la patogénesis de la enfermedad de Parkinson.

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