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Efecto de la lesión talámica estereotáctica en el temblor esencial
M Lakie1, L A Arblaster, R C Roberts
1Applied Physiology Research Unit, University of Birmingham, UK.
Lancet (London, England)
|July 25, 1992
Resumen
El temblor esencial (TE) es distinto del temblor fisiológico, lo que sugiere un generador central separado. Una lesión del tálamo alteró ET en una mano, apoyando su naturaleza independiente.
Área de la Ciencia:
- Neurología Neurología.
- La neurociencia es la neurociencia.
- Trastornos del movimiento Trastornos del movimiento.
Sus antecedentes:
- La etiología del temblor esencial (TE) sigue siendo desconocida.
- La relación entre ET (baja frecuencia) y el temblor fisiológico (alta frecuencia) no se entiende bien.
Objetivo del estudio:
- Investigar los mecanismos subyacentes del temblor esencial.
- Para determinar si el temblor esencial está relacionado con el temblor fisiológico.
Principales métodos:
- Se evaluó a un solo paciente con temblor esencial.
- Se realizó una lesión talámica estereotáctica.
- Se evaluaron las características del temblor antes y después del procedimiento.
Principales resultados:
- La lesión talámica estereotáctica redujo el temblor en la mano derecha pero no en la izquierda.
- Un componente de temblor de baja frecuencia persistió después de la lesión.
- Esto sugiere que el temblor esencial es una característica distinta superpuesta al temblor fisiológico.
Conclusiones:
- El temblor esencial parece provenir de un generador central autónomo.
- Este generador es independiente de los mecanismos subyacentes al temblor fisiológico.
- ET puede ser una característica adicional superpuesta al temblor fisiológico.
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