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Updated: Jul 14, 2026

Investigating the Spreading and Toxicity of Prion-like Proteins Using the Metazoan Model Organism C. elegans
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Investigating the Spreading and Toxicity of Prion-like Proteins Using the Metazoan Model Organism C. elegans

Published on: January 8, 2015

Juegos jugados por proteínas deshonestas en los trastornos priónicos y la enfermedad de Alzheimer

Adriano Aguzzi1, Christian Haass

  • 1Institute of Neuropathology, University Hospital of Zurich, Schmelzbergstrasse 12, CH-8091 Zurich, Switzerland. adriano@pathol.unizh.ch

Science (New York, N.Y.)
|November 1, 2003
PubMed
Resumen

La enfermedad de Alzheimer (AD) y los trastornos priónicos (PrD) comparten mecanismos comunes que involucran proteínas de la membrana neuronal como APP y PrPC. Comprender el mal plegamiento y la agregación de proteínas en una enfermedad puede avanzar en la investigación en la otra.

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