Search research articles

ACERCA DE JoVE

Visión General Liderazgo Blog Centro de Ayuda JoVE

AUTORES

Proceso de Publicación Consejo Editorial Alcance y Políticas Revisión por Pares Preguntas Frecuentes Enviar

BIBLIOTECARIOS

Testimonios Suscripciones Acceso Recursos Consejo Asesor de Bibliotecas Preguntas Frecuentes

INVESTIGACIÓN

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archivo

EDUCACIÓN

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Centro de Recursos para Profesores Sitio de Profesores

Términos y Condiciones de Uso

Política de Privacidad

Videos de Conceptos Relacionados

In-vitro Mutagenesis

In-vitro Mutagenesis

To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.

Plant Breeding and Biotechnology

Plant Breeding and Biotechnology

Crop cultivation has a long history in human civilization, with records showing the cultivation of cereal plants beginning at around 8000 BC. This early plant breeding was developed primarily to provide a steady supply of food.

Gene Conversion

Gene Conversion

Other than maintaining genome stability via DNA repair, homologous recombination plays an important role in diversifying the genome. In fact, the recombination of sequences forms the molecular basis of genomic evolution. Random and non-random permutations of genomic sequences create a library of new amalgamated sequences. These newly formed genomes can determine the fitness and survival of cells. In bacteria, homologous and non-homologous types of recombination lead to the evolution of new...

Genetic Screens

Genetic Screens

Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...

Evolutionary Processes in Microbes

Evolutionary Processes in Microbes

Microbial evolution occurs rapidly due to short generation times and a variety of genetic processes, including horizontal gene transfer, mutation, recombination, and genetic drift. These mechanisms collectively enable microbes to adapt swiftly to changing environments.Horizontal gene transfer (HGT) allows genes to move between different species and occurs through three main mechanisms: conjugation, transformation, and transduction. Conjugation involves direct cell-to-cell contact for DNA...

Evolution of New Traits in Microbes

Evolution of New Traits in Microbes

Microorganisms evolve rapidly due to their large population sizes and short generation times, often exhibiting measurable changes within days under laboratory conditions. Natural selection acts on standing genetic variation, enabling the retention and amplification of beneficial traits that confer fitness advantages in changing environments.Adaptive Pigment Regulation in RhodobacterIn Rhodobacter, a genus of purple non-sulfur bacteria, light-harvesting pigments such as bacteriochlorophyll and...

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por

Same author

Full spatio-temporal analyses of migration and colonization in evolution-dense 3D mapping of cancer metastases provides new insights.

Molecular biology and evolution·2026

Same author

Homoharringtonine is highly effective against SARS-CoV-2: a potential first-line defense in future coronavirus epidemics.

National science review·2025

Same author

Genomic evidence for males of exceptional reproductive output (ERO) in apes and humans.

National science review·2025

Same author

A map of enhancer regions in primary human neural progenitor cells using capture STARR-seq.

Genome research·2025

Same author

Characterization of cancer-driving nucleotides (CDNs) across genes, cancer types, and patients.

eLife·2024

Same author

The theory of massively repeated evolution and full identifications of cancer-driving nucleotides (CDNs).

eLife·2024

Search research articles

Video Experimental Relacionado

Updated: Jul 19, 2026

Fluorescence-microscopy Screening and Next-generation Sequencing: Useful Tools for the Identification of Genes Involved in Organelle Integrity

Fluorescence-microscopy Screening and Next-generation Sequencing: Useful Tools for the Identification of Genes Involved in Organelle Integrity

Published on: April 13, 2012

Adaptación ecológica durante la especiación incipiente revelada por el reemplazo genético preciso.

Anthony J Greenberg¹, Jennifer R Moran, Jerry A Coyne

¹Department of Ecology and Evolution, The University of Chicago, Chicago, IL 60637, USA.

Science (New York, N.Y.)

|December 6, 2003

Resumen

El gen desaturasa2 en las moscas de la fruta influye tanto en el comportamiento de apareamiento como en la supervivencia. Diferentes alelos están vinculados a la adaptación, lo que sugiere un papel en el proceso de especiación entre poblaciones distintas.

Más Videos Relacionados

Procedure for Adaptive Laboratory Evolution of Microorganisms Using a Chemostat

Procedure for Adaptive Laboratory Evolution of Microorganisms Using a Chemostat

Published on: September 20, 2016

Optogenetic Random Mutagenesis Using Histone-miniSOG in C. elegans

Optogenetic Random Mutagenesis Using Histone-miniSOG in C. elegans

Published on: November 14, 2016

Videos de Experimentos Relacionados

Last Updated: Jul 19, 2026

Fluorescence-microscopy Screening and Next-generation Sequencing: Useful Tools for the Identification of Genes Involved in Organelle Integrity

Fluorescence-microscopy Screening and Next-generation Sequencing: Useful Tools for the Identification of Genes Involved in Organelle Integrity

Published on: April 13, 2012

Procedure for Adaptive Laboratory Evolution of Microorganisms Using a Chemostat

Procedure for Adaptive Laboratory Evolution of Microorganisms Using a Chemostat

Published on: September 20, 2016

Optogenetic Random Mutagenesis Using Histone-miniSOG in C. elegans

Optogenetic Random Mutagenesis Using Histone-miniSOG in C. elegans

Published on: November 14, 2016

Área de la Ciencia:

Biología evolutiva Biología evolutiva.
Genética La genética.
Comportamiento animal Comportamiento animal.

Sus antecedentes:

Comprender el papel de la adaptación en la especiación requiere caracterizar las variaciones genéticas ecológicamente relevantes.
El gen desaturasa2 (ds2) en Drosophila melanogaster exhibe alelos geográficamente distintos relacionados con las diferencias feromonales entre las razas.

Objetivo del estudio:

Para investigar los efectos fenotípicos de alelos específicos de desaturasa2 (ds2).
Determinar si los alelos ds2 contribuyen a la adaptación ecológica y al aislamiento reproductivo en Drosophila melanogaster.

Principales métodos:

Utilizó reemplazo genético dirigido al sitio para introducir un alelo Zimbabwe ds2 en Cosmopolitan D. melanogaster.
Se mantuvieron antecedentes genéticos idénticos para aislar los efectos del gen ds2.

Principales resultados:

El alelo Cosmopolitan ds2 confería resistencia a las bajas temperaturas.
El alelo Cosmopolitan ds2 también resultó en una mayor susceptibilidad a la inanición.

Conclusiones:

La adaptación ecológica, específicamente la resistencia al frío y la susceptibilidad al hambre, se asocia con el gen desaturasa2.
Estos hallazgos sugieren que la adaptación ecológica puede acompañar el aislamiento sexual entre las razas conductuales de Zimbabwe y Cosmopolitan de D. melanogaster.