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Dinámica epigenética de la inactivación de la X impresa durante el desarrollo temprano del ratón

Ikuhiro Okamoto1, Arie P Otte, C David Allis

  • 1CNRS UMR218, Curie Institute, 26 rue d'Ulm, Paris 75005, France.

Science (New York, N.Y.)
|December 13, 2003
PubMed
Resumen

El cromosoma X paterno se imprime e inactiva temprano en el desarrollo del ratón, antes de la diferenciación. Este estado inactivo se invierte más tarde en la masa celular interna, mostrando plasticidad de inactivación X.

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