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Updated: Jul 17, 2026

Using Reverse Genetics to Manipulate the NSs Gene of the Rift Valley Fever Virus MP-12 Strain to Improve Vaccine Safety and Efficacy
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Using Reverse Genetics to Manipulate the NSs Gene of the Rift Valley Fever Virus MP-12 Strain to Improve Vaccine Safety and Efficacy

Published on: November 1, 2011

Los efectos protectores de una vacuna SIV viva atenuada con una deleción en el gen nef

M D Daniel1, F Kirchhoff, S C Czajak

  • 1New England Regional Primate Research Center, Harvard Medical School, Southborough, MA 01772.

Science (New York, N.Y.)
|December 18, 1992
PubMed
Resumen

Desarrollar una vacuna contra el virus de la inmunodeficiencia humana (VIH) es un desafío. Los investigadores descubrieron que la eliminación del gen nef del virus de la inmunodeficiencia simiana (SIV) creó una vacuna atenuada segura y viva que protegió a los monos del SIV. patógeno.

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