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Reflectinas: las inusuales proteínas de los tejidos reflectantes de los calamares

Wendy J Crookes¹, Lin-Lin Ding, Qing Ling Huang

¹Kewalo Marine Laboratory, Pacific Biomedical Research Center, University of Hawaii-Manoa, 41 Ahui Street, Honolulu, HI 96813, USA.

Science (New York, N.Y.)

|January 13, 2004

Resumen

Las reflectinas de los calamares son proteínas únicas que forman plaquetas estructurales en tejidos que reflejan la luz. Su composición inusual y sus dominios conservados resaltan la nanofabricación animal.

Área de la Ciencia:

La bioquímica es la bioquímica.
Biología Molecular Biología Molecular
Fisiología Animal Fisiología Animal

Sus antecedentes:

Los calamares poseen tejidos especializados para la manipulación de la luz.
La base molecular de estos tejidos reflectantes no se entiende completamente.

Objetivo del estudio:

Para identificar y caracterizar las proteínas responsables de la reflexión de la luz en los calamares.
Investigar la base genética y las propiedades estructurales de estas nuevas proteínas.

Principales métodos:

Análisis y secuenciación de proteínas.
Identificación de la familia de genes.
Análisis comparativo de secuencias. análisis comparativo de secuencias.

Principales resultados:

Descubrimiento de las reflectinas, una nueva familia de proteínas únicas de los calamares.
Las reflectinas están codificadas por al menos seis genes y cuentan con cinco dominios de repetición conservados.
Estas proteínas exhiben una inusual composición de aminoácidos, ricos en tirosina, metionina, arginina y triptófano.

Conclusiones:

Las reflectinas son la base estructural de las plaquetas reflectoras de luz en los calamares.
La composición única y los dominios conservados sugieren una función especializada en la manipulación de la luz.
Las reflectinas de los calamares representan un notable ejemplo de nanofabricación biológica.

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