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Características del flujo pulsátil de los heterografos porcinos de la válvula aórtica en el hombre
L G Christie1, W W Nichols, C J Pepine
1Division of Cardiology, University of Florida College of Medicine, Shands Teaching Hospital, Gainesville, Florida 32610, USA.
Circulation
|September 1, 1978
Resumen
Los heterogrifos aórticos porcinos fijados con glutaraldehído demuestran excelentes características de flujo pulsátil en la aorta ascendente, imitando de cerca las válvulas normales. Esto sugiere un rendimiento favorable a largo plazo para esta válvula aórtica protética.
Área de la Ciencia:
- Cirugía cardiovascular La cirugía cardiovascular es una cirugía cardiovascular.
- Ingeniería Biomédica Ingeniería Biomédica.
- La hemodinámica es la hemodinámica.
Sus antecedentes:
- El reemplazo de la válvula aórtica (AVR) es un procedimiento común para la enfermedad grave de la válvula aórtica.
- La evaluación del rendimiento hemodinámico de las válvulas protésicas es crucial para los resultados de los pacientes.
- Los heterogreftos porcinos son válvulas prostéticas utilizadas con frecuencia.
Objetivo del estudio:
- Para evaluar las características del flujo pulsátil en la aorta ascendente después de la AVR utilizando heterografías porcinas fijadas en glutaraldehído.
- Para comparar estas características de flujo con las de las válvulas aórticas normales.
Principales métodos:
- Se examinaron 14 pacientes 12 meses después de la AVR con trasplantes heterogéneos porcinos.
- Se analizaron las señales de velocidad para medir la velocidad máxima, la aceleración máxima, el volumen de la carrera y el tiempo de eyección.
- Utilizó técnicas angiográficas para la visualización del flujo sanguíneo.
- Parámetros de flujo comparados con un grupo de control de 8 pacientes con válvulas aórticas normales.
Principales resultados:
- Los gradientes aórticos valvales fueron mínimos en los pacientes con la válvula prostética.
- Los parámetros de velocidad de flujo pulsátil en la aorta ascendente eran casi indistinguibles de los de los pacientes con válvulas aórticas normales.
- La angiografía mostró patrones de flujo sanguíneo similares entre los grupos.
Conclusiones:
- Los heterogrifos aórticos porcinos fijados con glutaraldehído exhiben un rendimiento hemodinámico comparable al de las válvulas aórticas nativas.
- La similitud en las características de flujo sugiere la posibilidad de una función favorable a largo plazo de esta válvula protética.
- Este heteroinjerto porcino es un fuerte candidato para la cirugía de reemplazo de válvula aórtica.
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