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Enfermedad estreptocócica del grupo B en bebés del Reino Unido e Irlanda menores de 90 días
Paul T Heath1, Gail Balfour, Abbie M Weisner
1Vaccine Institute, St George's Hospital, London, UK. pheath@sghms.ac.uk
Lancet (London, England)
|January 31, 2004
Resumen
Las infecciones por estreptococos del grupo B (GBS) en los bebés son una preocupación significativa. Este estudio revela una incidencia mínima de 0,72 por cada 1000 nacidos vivos en el Reino Unido e Irlanda, con una tasa de mortalidad del 9,7%.
Área de la Ciencia:
- Salud Neonatal La salud neonatal es la salud neonatal.
- Enfermedades infecciosas Enfermedades infecciosas.
- Epidemiología La epidemiología.
Sus antecedentes:
- La enfermedad estreptocócica del grupo B (GBS) representa una amenaza significativa para la salud infantil.
- Los datos sobre la incidencia, morbilidad y mortalidad del GBS en el Reino Unido y la República de Irlanda eran previamente limitados.
Objetivo del estudio:
- Para determinar la incidencia, morbilidad y mortalidad de la enfermedad invasiva del SGB en bebés menores de 90 días de edad.
- Para establecer la carga actual de la enfermedad de GBS en la población infantil del Reino Unido e Irlanda.
- Proporcionar datos para el desarrollo de directrices de prevención del GBS.
Principales métodos:
- Se realizó un estudio de vigilancia entre el 1 de febrero de 2000 y el 28 de febrero de 2001.
- Los casos invasivos de GBS en bebés menores de 90 días fueron identificados a través de una red de pediatras, microbiólogos y padres.
- Se calcularon las tasas de incidencia para la enfermedad GBS general, de inicio temprano y de inicio tardío.
Principales resultados:
- Se identificaron un total de 568 casos de GBS, lo que equivale a una incidencia general de 0,72 por cada 1000 nacidos vivos.
- La incidencia de la enfermedad por SGB de inicio temprano fue de 0,48 por cada 1000 nacidos vivos (377 casos), y la incidencia de inicio tardío fue de 0,24 por cada 1000 nacidos vivos (191 casos).
- La tasa de mortalidad general fue del 9,7% (53 muertes), y los factores de riesgo identificables estuvieron presentes en el 58% de los casos de aparición temprana.
Conclusiones:
- El estudio estableció la carga mínima de la enfermedad GBS invasiva en bebés del Reino Unido e Irlanda.
- Los hallazgos destacan el impacto sustancial de la GBS en la salud neonatal.
- Los datos son cruciales para informar y formular estrategias efectivas de prevención de la enfermedad por SGB.
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