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La asignación de resonancias de protones de campo inferior en un complejo inhibidor de enzimas utilizando saturación

Hua Deng1, Sean Cahill, Linda Kurz

  • 1Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA. hdeng@aecon.yu.edu

Journal of the American Chemical Society
|February 20, 2004
PubMed
Resumen

La saturación dependiente del tiempo transferida NOE (STNOE) asignó con éxito resonancias de protones en adenosina deaminasa-purina ribósido. Este método detecta los cambios estructurales del inhibidor de enzimas e identifica los protones enlazados con hidrógeno en los complejos.

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