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Updated: Jul 16, 2026

Using Caco-2 Cells to Study Lipid Transport by the Intestine
07:00

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Published on: August 20, 2015

Niemann-Pick C1 Like 1 La proteína es crítica para la absorción del colesterol intestinal

Scott W Altmann1, Harry R Davis, Li-Ji Zhu

  • 1Department of Cardiovascular/Endocrine Research, Schering-Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, NJ, 07033-0539, USA. scott.altmann@spcorp.com

Science (New York, N.Y.)
|February 21, 2004
PubMed
Resumen

La proteína Niemann-Pick C1 Like 1 (NPC1L1) es crucial para la absorción del colesterol en el intestino. El bloqueo de NPC1L1 con ezetimiba reduce efectivamente la absorción de colesterol, destacando su papel en el control de los niveles de colesterol en el plasma.

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