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Updated: May 7, 2026

Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists
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Un complejo de intercambio corepresor/coactivador requerido para la activación transcripcional por los receptores

Valentina Perissi1, Aneel Aggarwal, Christopher K Glass

  • 1Howard Hughes Medical Institute, Department of Molecular Medicine, School of Medicine, University of California, San Diego, La Jolla 92093, USA.

Cell
|February 26, 2004
PubMed
Resumen

Dos proteínas, TBL1 y TBLR1, son cruciales para cambiar los genes de represión a activación. Estos factores facilitan el intercambio de corepresores por coactivadores, esenciales para la transcripción mediada por los receptores nucleares.

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