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Formación fotoquímica altamente eficiente de 2'-deoxirribonolactona en el bucle diagonal de un cuarteto G

Yan Xu1, Hiroshi Sugiyama

  • 1Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Chiyoda, Tokyo 101-0062, Japan.

Journal of the American Chemical Society
|May 20, 2004
PubMed
Resumen

Este estudio revela que el 5-iodouracilo en las estructuras de ADN del cuarteto G antiparalelo forma específicamente 2'-deoxyribonolactona. Esta reacción fotoquímica, que ocurre en el bucle diagonal, puede servir como una sonda para estas estructuras de ADN.

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