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Updated: Jul 18, 2026

A Strategy for Sensitive, Large Scale Quantitative Metabolomics
14:18

A Strategy for Sensitive, Large Scale Quantitative Metabolomics

Published on: May 27, 2014

1,4-hidrosilaciones asimétricas de ésteres alfa y beta insaturados

Bruce H Lipshutz1, Jeff M Servesko, Benjamin R Taft

  • 1Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106, USA. lipshutz@chem.ucsb.edu

Journal of the American Chemical Society
|July 9, 2004
PubMed
Resumen

El hidruro de cobre catalítico (CuH) con ligandos JOSIPHOS o SEGPHOS permite reducciones altamente enantioselectivas de 1,4-de enoatos y lactonas. Este método logra una proporción excepcional de sustrato a ligando de 7700:1, mostrando una eficiencia notable.

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