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Infección por VIH, infección por hepatitis C y HAART: opciones clínicas difíciles
Shyam Kottilil1, Michael A Polis, Joseph A Kovacs
1Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md, USA.
JAMA
|July 14, 2004
Resumen
La hepatotoxicidad es una complicación común en pacientes con el virus de la inmunodeficiencia humana (VIH) en terapia antirretroviral altamente activa (HAART). El manejo de los problemas hepáticos requiere considerar el HAART, el abuso de sustancias y las coinfecciones virales como el virus de la hepatitis C (HCV) o el virus de la hepatitis B (HBV).
Área de la Ciencia:
- Hepatología Hepatología.
- Enfermedades infecciosas Enfermedades infecciosas.
- Farmacología Farmacología.
Sus antecedentes:
- La disfunción hepática es una complicación frecuente en las personas infectadas por el virus de la inmunodeficiencia humana (VIH) que se someten a terapia antirretroviral altamente activa (HAART).
- La enfermedad hepática contribuye significativamente a la morbilidad y mortalidad en la población VIH-positiva.
- Comprender las causas multifactoriales de la hepatotoxicidad es crucial para el manejo del paciente.
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