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Updated: May 2, 2026

Assaying the Ability of Diffusible Signaling Molecules to Reorient Embryonic Spinal Commissural Axons
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Assaying the Ability of Diffusible Signaling Molecules to Reorient Embryonic Spinal Commissural Axons

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Ir a la distancia, o no, con las señales de las neurotrofinas

Louis F Reichardt1, William C Mobley

  • 1Program in Neuroscience, Department of Physiology and Howard Hughes Medical Institute, University of California, San Francisco, 1550 Fourth Street, Room 284A, San Francisco, CA 94143, USA.

Cell
|July 21, 2004
PubMed
Resumen

El factor de crecimiento nervioso (NGF) y la neurotropina-3 (NT-3) señalan a través de los receptores TrkA, pero solo el NGF promueve la supervivencia de las neuronas. Esta diferencia se debe a la capacidad del NGF para desencadenar la internalización del receptor TrkA y el transporte retrógrado, a diferencia del NT-3.

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