Derepresión por despolimerización; conocimientos estructurales sobre la regulación de Yan por Mae.

Feng Qiao1, Haiyun Song, Chongwoo A Kim

  • 1UCLA-DOE Institute of Genomics and Proteomics, Molecular Biology Institute, Department of Chemistry and Biochemistry, University of California, Los Angeles 90095, USA.

Cell
|July 21, 2004
PubMed
Resumen

La proteína Mae despolimeriza Yan, un represor de la transcripción, a través de su dominio SAM. Este nuevo mecanismo permite a Mae regular la actividad de Yan, impactando la señalización de la tirosina quinasa del receptor.

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