Impacto de la flexibilidad de las proteínas en los parámetros de transferencia de hidruro en las deshidrogenases de

Zhao-Xun Liang1, Iason Tsigos, Vassilis Bouriotis

  • 1Departments of Chemistry and Molecular and Cell Biology, University of California, Berkeley, California 94720, USA.

Resumen

La deshidrogenasa de alcohol termófilo (htADH) muestra parámetros cinéticos distintos en comparación con la deshidrogenasa de alcohol psicófilo (psADH). La dinámica de las proteínas, específicamente la flexibilidad local, es crucial para los procesos de transferencia de hidruro en estas enzimas.

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